When Apple dropped 32-bit application support with Catalina and introduced stricter security protocols (notarization requirements), the legacy Radium drivers ceased to function. Installing them on macOS Ventura or Sonoma will result in installation failures, kernel extension blocking errors, or the system simply not recognizing the device in Audio MIDI Setup.
The M-Audio Radium 49 is a 49-key semi-weighted MIDI keyboard controller featuring 16 backlit MPC-style pads, 8 assigned controllers, and a built-in arpeggiator. It's compatible with both Mac and PC platforms and can be used with a variety of music production software, including Ableton Live, Logic Pro, and more. m-audio radium 49 driver mac
M-Audio has discontinued support for the Radium series. You cannot install a manufacturer driver on macOS Catalina or newer. When Apple dropped 32-bit application support with Catalina
By manually setting these to standard numbers, you can often "trick" your DAW into recognizing them even without the official driver, using the DAW's "MIDI Learn" function (usually Command + L in Logic Pro, or the wrench icon in Ableton Live). It's compatible with both Mac and PC platforms
If you are running an (High Sierra, Mojave, or earlier), you can still use the final official drivers. Below is the official driver history for the Radium 49.