A Mab A Case Study In Bioprocess Development -

principles can be applied to develop a monoclonal antibody (mAb)

Butyl Sepharose – used only if aggregates > 1.5% after CEX. A Mab A Case Study In Bioprocess Development

The team chose (Chinese hamster ovary) cells, the industry workhorse. For A Mab, they used a glutamine synthetase (GS) knockout system to eliminate ammonia build-up and enable selection with methionine sulfoximine (MSX). principles can be applied to develop a monoclonal